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( i ) Confocal images of mitochondria (imaged by TOM20 staining) and mtDNA in cells treated with 5FU for 72 h

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Biochimica et Biophysica Acta, 1812 , 663673

Interestingly, in individuals with HVDAS, the ADNP-SIRT1-EB1/EB3 protein complex may regulate autophagy, which is dysregulated and negatively affects mitochondrial metabolism in autism [344]