why do you need to have b12 injections Shots for Weight Loss: What Know The Science Behind Vitamin B12:

A body might react adversely to B12 shots for a variety of reasons

What should I avoid while using vitamin B12 injection

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This is general reference material, not personalized medical advice

A single B12 injection can remain in your system for several weeks because the liver stores B12 for later use

In that specific situation, B12 injections can aid in weight loss indirectly, by helping someone feel well enough to be more active and consistent with their routine