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The muscle is being used too much and ends up needing more resources sent to it, like blood carrying oxygen

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the purpose of elongating the N-terminal acyl group and removing the N-terminal amino group was to increase the probability that resultant molecules might be BBB permeable and access the brain parenchyma

Figure 8 Discussion We show that the HGF mimetic Dihexa protects lateral line hair cells from acute aminoglycoside ototoxicity