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No large human randomized controlled trial exists for either compound in any musculoskeletal use

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Dihexa has also been patented for potential use in treating Alzheimers and Parkinsons disease, though human clinical evidence remains in early stages

Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs

Simultaneously, it upregulated 10 caspase genes (which eliminate damaged cells) and activated 84 DNA repair genes suggesting a powerful cell-protective function