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However, the lower extent of ROS keeps the cell in a reduced state and can be employed as a second messenger participating in cell division and differentiation, stem cell maintenance, organogenesis as well as maintenance of stress responses [45]

doi:10.1016/j.freeradbiomed.2012.05.025, PMID: 22634394 Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD (2009) Novel role for glutathione S -transferase piRegulator of protein S-glutathionylation following oxidative and nitrosative stress

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