The investigation was triggered by case studies of two women who had skin irritations that disappeared when they stopped eating gluten in their diets and stopped using cosmetic products containing gluten
Stacking does not multiply the regulatory or safety concerns of either compound but does compound the research-only status of both - neither has FDA or EMA approval, and TB-500 specifically is on the WADA Prohibited List
In patients with locally advanced, metastatic, and/or refractory solid tumors and hematological malignancies, CB839 is being evaluated in open-label phase I clinical trials (NCT02071862, NCT02071888, NCT02771626)
Garrido C, Brunet M, Didelot C, Zermati Y, Schmitt E, Kroemer G
Once they had assembled the full body of evidence, they applied multivariable linear regression analysis to the pooled data
Diabetes, metabolic syndrome and obesity : targets and therapy