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Am J Med Genet A

Trescot, A

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In addition, participants were strongly encouraged to fast on the day of the MR scan to minimize potential effects of food intake [48, 49] (one individual with ASD could not follow the instruction and had a light meal)

Upon proteolytic degradation, these residues undergo a series of enzymatic reactionsincluding hydroxylation, aldol cleavage, and aldehyde oxidationleading to the formation of 4-trimethylaminobutyric acid (-butyrobetaine), which is subsequently converted into l-carnitine through the catalytic action of -butyrobetaine dioxygenase (BBOX1) 25,26