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The future research should focus on evaluating the effectiveness of hepatology-led cessation interventions and their long-term impact on liver health

A Cerami designed the trial, participated in data analysis and wrote the paper

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3g, GS siRNA transfection, which led to more than 60% GS gene silencing, similarly increased the sensitivity of hepatocytes to TNF killing, suggesting that increased GSSG accumulation mechanistically contributed to cellular glutathione imbalance-induced susceptibility to TNF-induced cell death

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More recent findings suggest that ferroptosis, the iron accumulation-related and lipid peroxidation-driven type cell death pathway [9, 10], plays an important role in AD pathology [11]