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An inherited form of hyperhomocysteinemia results from mutations in the methylene tetrahydrofolate reductase (MTHFR) gene

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A preclinical study showed that V-9302 could selectively block Gln uptake by TNBC cells, promote the activation of CD4 + T cells and CD8 + T cells, and reduce the level of Treg in a TNBC mouse model

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Open studies could not control expectation or placebo effects

ROS production by neutrophils correlates with the severity of the reactivity of airways [27]