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Forests 12(10):1404 Reiter RJ (1995) Oxygen radical detoxification processes during aging: the functional importance of melatonin

12 Although these compounds are beneficial in the free form, it was also confirmed that when bound to lens proteins, as occurs with increasing age in the lens nucleus, these UV filters become stronger photosensitizers which can, in the presence of oxygen and UV radiation, generate singlet oxygen, superoxide anion, and hydrogen peroxide within the lens nucleus 24 Hydrogen peroxide, although producing little direct damage, can be converted into highly reactive and damaging species in the presence of transition metals

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