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Starting Dose 0.3 mg In the phase 2 weight study, dosing started low at 0.3 mg weekly and was raised every 2 weeks to reduce nausea [1]

Disclosure of interest: All authors declare no conflict of interest

AOD-9604 Dosage and Cycling: Injection Timing, Fasted Cardio Stack, and Maintenance (2026) AOD-9604 Dosage: What the Clinical Data Actually Says AOD-9604 dosage in clinical research ranged from 250 mcg to 10 mg daily, with the 1 mg/day arm producing the best documented weight loss result: 2.6 kg over 12 weeks versus 0.8 kg placebo

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Additionally, approximately 20.9% of retatrutide users at 12 mg experienced dysesthesia (skin sensitivity/tingling), a side effect not seen with tirzepatide

Slower Digestion GLP-1 medications slow gastric emptying, helping you feel full longer after eating