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In addition to movement disorder, different non-motor symptoms such as dementia, psychosis and depression are observed in patients, which increase in late stages of disease

doi: 10.1016/j.intimp.2024.113136 46 ZhangJWuSXuYZhangLCongCZhangMet al

8(1): 15-21. Published online 2018 Jan 31

Mumtaz MA, Hao Y, Mehmood S, Shu H, Zhou Y, Jin W, et al

showed that fucoidan could help adult male (68 weeks) C57BL/6 J mice who were depressed: those who were exposed to lipopolysaccharide (LPS) and those who were under chronic restraint stress