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PI3K/Akt/mTOR Signaling Cascade A primary downstream pathway of IGF-1R activation is the PI3K/Akt/mTOR cascade, which regulates cell survival, protein synthesis, and metabolic homeostasis

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Not only a key part of table salt (sodium chloride), chloride is a part of common mineral compounds like potassium chloride and calcium chloride that also impart a salty flavor to water

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