Studies have estimated an adult dose of -lipoic acid up to 2400 mg with no severe side effects
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doi: 10.1002/mnfr.200600145, 111
Sajdel-Sulkowska EM, Lipinski B, Windom H, Audhya T, McGinnis W
( A C ) TNBC metastatic 4T07 and 4T1 ( A ), D2A1-m1 and D2A1-m2 ( B ), human MDA-MB-468 and MDA-MB-231 ( C ) cells were pre-treated with 10 M FADS2i (SC-26196), FADS1/2i (CP-24879), and SCD1i (CAY10566) for 4 h, exposed ON to 0.5 M erastin, and subjected to cell viability assay ( n = 3 biological replicates in either single, duplicate or technical triplicate)