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6 Conclusion The growing prevalence of resistance to first- and second-line antibiotics, in the absence of an effective preventative strategy necessitates the need for alternative therapies that can reduce the enormous disease burden associated with NTHi infections

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12 , e1005679 (2016)

Even athletic anti-doping programs do not prohibit topical cosmetic use

"A systematic review of microbiome changes and impact of probiotic supplementation in children and adolescents with neuropsychiatric disorders."

However, the intermediate link is dysregulated in the pathological state, leading to mitochondrial dysfunction and insufficient energy supply to chondrocytes, which stimulates pathological changes (52)