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For instance, ADCs utilizing non-cleavable linkers have been associated with significant ocular toxicity, as seen with tisotumab vedotin, indicating that the released payload metabolite can still affect sensitive tissues [36]

Standard toxicology screens and prenatal panels do not include synthetic peptide detection, meaning exposure confirmation relies on patient disclosure rather than biomarker testing

Phagocytes and oxidative stress

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222 , e202207097 (2023)