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4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation

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Drop back to the last tolerated dose and stay there for 6-8 weeks before attempting escalation again

The combination of autophagosome isolation and quantitative proteomics has identified nuclear receptor coactivator 4 (NCOA4) as the cargo receptor responsible for autophagy-dependent ferritin degradation (52)

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