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People on blood thinners bruise more easily and should mention it beforehand

But even then, it should be understood as an experimental deviation from the standard, not the default

This enzyme wastes a helpful molecule called nicotinamide (a form of vitamin B3) by turning it into something useless instead of recycling it into NAD+, think of NAD+ as the main battery fuel that powers your cells energy factories (mitochondria)

[PMC free article: PMC3465509] [PubMed: 22920894] (Hypothesis that high doses of acetaminophen might cause modifications of PDH that could induce autoantibody [AMA] formation and that drugs or environmental toxins may play a pathogenetic role in primary biliary cirrhosis)

10.1016/S0015-0282(98)00208-8 88 MaruoT.OharaN.MatsuoH.XuQ.ChenW.Sitruk-WareR.et al (2007)

J Chemother