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The interaction between endothelial CD93 and MMRN2 regulates fibronectin deposition during glioma angiogenesis, and loss of endosialin, mainly expressed in pericytes, protects against development of fibrosis, suggesting that this protein family participates in regulating the extracellular matrix [105, 109]

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Use within 30 days of reconstitution for optimal stability

Am J Hematol 97(7):885-894, 2022

A large preclinical toxicity program run across mice, rats, rabbits, and dogs found BPC-157 well tolerated with no serious treatment-related toxicity, no identifiable lethal dose, and no genotoxic or teratogenic signal, which is the strongest safety data point available by Xu 2020