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There was also no long-term follow-up to assess if any delayed complications (for example, abnormal tissue growth or tumor formation) occurred after the injection

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Research applications of the KLOW combination include investigation of multi-modal tissue repair mechanisms, studies of peptide synergism and interaction effects, examination of copper-peptide delivery systems, and exploration of combined anti-inflammatory and regenerative approaches

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Some animal studies, such as one involving a segmental bone defect in rabbits (Sebecic et al., 1999), explored its local application

Evidence and Procedure Any classification change request must be supported by strong evidence that demonstrates the risk to the public will be adequately managed