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In an in vitro study, it was found that low concentration of 5-FU selectively destroys keratinocytes within 3 weeks, whereas melanocytes multiply, leading to repigmentation

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The dose escalation schedule followed a gradual increase pattern designed to minimize gastrointestinal side effects while allowing researchers to identify optimal therapeutic ranges

[DOI] [PMC free article] [PubMed] [Google Scholar] 202.Rashida Gnanaprakasam J.N., Wu R., Wang R

Some studies have shown no change in glutathione levels or measurements of oxidative stress despite ongoing glutathione supplementation [36]

It is widely studied in scientific and laboratory settings for its potential roles in cell signaling, tissue remodeling, and regenerative pathways