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Currently, measurement of D-antigen content in IPV vaccines relies on the use of D-antigen-specific monoclonal antibodies (mAbs) provided by the National Institute for Biological Standards and Control (NIBSC), including mAb234 for PV1, mAb1050 for PV2, and mAb520 for PV3

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In a specific systemic context, supplementation with Bifidobacterium animalis subsp

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2022HX152) and the Doctoral Scientific Research Foundation of Hubei University of Science and Technology (grant no