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Acute SIRT2 inhibition affects mTORC1-dependent protein synthesis in NRCMs Since our in vitro results demonstrate that SIRT2 is a negative regulator of protein synthesis, and Sirt2 -KO mice hearts exhibit upregulated protein synthesis concomitant with increased mTORC1 activity, we wanted to investigate whether acute SIRT2 manipulation has a similar effect in cardiac cells

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PMID: 38205450 19 Megaloblastic Anemias: Nutritional and Other Causes

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Ginger extracts (3 and 10 micrograms/milliliter, g/mL) significantly suppressed PGE 2 production, while it also suppressed NO production at 100g/mL