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Potential benefits of probiotics and prebiotics for coronary heart disease and stroke

Magdalna Krulov and Libor Mike are acknowledged for fruitful discussions and/or critical reading of the manuscript

The methionine remethylation step can be facilitated by several intermediates such as the well known reaction mediated by folic acid and its active metabolites to form 5-methyltetrahydrofolate (5-MTHF) creating tetrahydrofolate (THF) which will then regenerate to 5-MTHF through the action of methylenetetrahydrofolate reductase (MTHFR)

Once depleted, cells lose their ability to neutralize reactive oxygen species, defend against ferroptosis, support proper iron metabolism, and maintain immune and neurological function

Prescriptions are based on patient eligibility, and patient-specific compounding needs

When glucose transport is impaired, the body stores glycogen and fat because it cannot use all the energy, resulting in weight gain [7]