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Folic acid in very high doses can hide ongoing B12 deficiency
As a result, translation to surgical recovery and perioperative decision-making remains unsupported by high-quality clinical evidence
Older individuals: Aging leads to decreased gastric acid production, reducing B-12 release from bound proteins
Standard dosing protocol Dose range : 1-3mg daily Most common : 2mg daily for therapeutic use Conservative start : 1mg daily for first week, assess tolerance High dose : 3mg daily for acute inflammation or intensive healing Frequency : Once daily, preferably same time each day Reconstitution Standard protocol : Add 2ml bacteriostatic water to 50mg vial Concentration : 25mg/ml Dose calculation examples : 1mg dose = 0.04ml (4 units on insulin syringe) 2mg dose = 0.08ml (8 units) 3mg dose = 0.12ml (12 units) 50mg vial lasts : 25-50 days depending on dose Use our reconstitution calculator for exact measurements
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