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The mid-phase remodeling period (days 3-14) exhibits maximum benefits from enhanced cellular migration, proliferation, and matrix deposition

HR = 2.42 (95% CI = 1.45 to 4.04) particularly with only delivery of -tocopherol (HR = 2.88, 95% CI = 1.56 to5.31) (20)

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doi: 10.1182/blood-2004-02-0446 113 SimardJCSimonMMTessierPAGirardD

Taken chronically, however, it can disrupt those dopamine pathways