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A systematic review of prolotherapy for chronic musculoskeletal pain

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cGMP, in turn, activates cGMP-dependent protein kinase resulting in membrane hyperpolarization and subsequent vasodilatation

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Its frequency continues to rise, affecting approximately 1% of the general population and more than 5% of workers in specific industries that involve repetitive hand and wrist movements, with a female-to-male ratio of approximately 3:1