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The animals were kept in a 12-hour light/dark cycle and maintained on standard rat laboratory chow and tap water ad libitum

In follow-up of the in vitro data, Doxorubicin progressively induced senescence in vivo as detected by p16 ink4a -driven RLUC in p163MR mice (Fig

Oncotarget .Read source Pickart L, Margolina A (2018)

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Some researchers find the larger injection volumes less comfortable, especially for daily protocols, though retatrutide is administered weekly which makes this less of a concern