GHK-Cu is predominantly found in saliva, blood, and urine, and has multiple biological actions when administered to test subjects, including [1]: Antioxidant gene activity [2] Suppression of inflammatory cytokine interleukin-6 [2] Increased protein accumulation [3] Increased collagen synthesis [3] In animal models, GHK-Cu has been shown to increase an anti-inflammatory proteogly called decorin that can protect diabetic rats from kidney-damaging fibrosis [2, 4]
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(PubMed) Ying Z, Kampfrath T, Sun Q, Parthasarathy S, Rajagopalan S
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Gene signature analysis via Connectivity Map reveals broad regenerative profile Overlapping expression patterns with anti-fibrotic and anti-inflammatory compounds Suggests neuroprotective and anti-cancer research potential beyond skin repair GHK peptide induces neural differentiation in human bone-marrow-derived mesenchymal stem cells, demonstrating neurogenic potential relevant to neuroscience and regenerative medicine research
