For instance, pre-illness dietary factors such as high fat intake, reduced consumption of fiber, excessive red meat, alcohol, and low levels of short-chain fatty acids (SCFAs) have been associated with an increased risk of adenomas and CRC
Oral F.n translocate to the intestine by resisting the acidic environment at pH 1.5 owing to the presence of erucic acid in its cell membrane, which is regulated by FnFabM, increasing its colonization efficiency in the stomach and jejunum of mice (Li et al., 2025)
Nat Chem Biol
For example, sortase-dependent pili mediate mucosal adhesion via SpaC subunit binding
These findings indicate that adding reduced glutathione to entecavir therapy could be a highly effective approach for managing chronic hepatitis B, particularly for improving liver function and accelerating viral clearance
Genetics, blood pressure, cholesterol, diabetes, smoking, kidney function, age, and lifestyle remain major determinants of cardiovascular risk