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When ARA-290 binds to the IRR, it does two critical things: It shuts down inflammation: It tells the immune system to stop attacking the damaged area, switching the focus from "defense" to "reconstruction." It stimulates regeneration: It promotes the sprouting of small nerve fibers, which are often the first to die in conditions like Small Fiber Neuropathy (SFN)
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The fluffy white powder can be stored at room temperature until it is ready to be reconstituted with bacteriostatic water
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Analysis of the synovial tissue and popliteal lymph nodes (pLN) by flow cytometry analysis at this early time points (25 days after immunization) did not reveal any changes in the total synovial CD4 + T-cell or B220 + B-cell frequencies (Supplementary Fig
