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Intermittent claudication: Propionyl-L-carnitine (PLC) 2 g once daily in patients with peripheral artery disease, combined with exercise training and other strategies

The NRP-1-mediated SARSCoV2 entry into bone marrowderived macrophages (BMM) could impede osteoclast differentiation and affect calcium/phosphorus metabolism in COVID19 patients 328

First-pass hepatic metabolism degrades an estimated 6085% of the compound before systemic circulation, requiring oral doses 35 times higher than parenteral routes to achieve comparable plasma concentrations

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