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Synergistic interactions between GSTs and efflux pumps have also been observed in several studies 68,70

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Cells were incubated with QIs or parent compounds for 2.5 h, based on the time-dependency of QIs-induced loss of cell viability (Supplementary Figure S3)

When intracellular GSH levels were depleted activation of caspase 3 was less, being 30 and 40% for AQ-QI and DEAQ-QI, respectively

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While topical treatments can help, true radiance starts from within