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Elsayed YY, Khl T, Imhof D

A metabolome analysis disclosed that sulphasalazine triggers an increase in the glutamate-derived TCA cycle intermediate -ketoglutarate in addition to a decrease in cysteine and glutathione

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The aforementioned mechanisms suggest that Pheretima aspergillum and its compound formulations can modulate neuroinflammation and microcirculatory dysfunction, offering a potential therapeutic strategy for mitigating oxidative damage in brain tissue, and restoring the BBB function under high-altitude hypoxic conditions

A root-cause approach that focuses on gut health, anti-inflammatory diet, and lifestyle modifications

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