One intriguing recent discovery is that gut microbes can produce small amounts of ammonia and other compounds that affect brain metabolism: a 2025 study showed that manipulating the gut microbiome altered brain amino acid levels and stress susceptibility in mice, partly via microbe-derived ammonia affecting neurotransmitter cycling [88]
It works without the use of drugs or chemicals
PubMed Search Google Scholar Export Citation Sztretye, M., Dienes, B., Gnczi, M., Czirjk, T., Csernoch, L., Dux, L., Szentesi, P., & Keller-Pintr, A
Gram-negative bacterial lipopolysaccharide (LPS) stimulates macrophages to produce IL-6 and IL-1, two cytokines that increase BBB permeability and are associated with seizure progression (136)
The average human consumes anywhere from 150-200 mg of CLA a day and studies show a total of 3400-6800mg of CLA can and should be consumed for added improved body composition
First, complementary actions where peptides target different aspects of the same process