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A reduction in Numeric Rating Scale (NRS) for arm pain (0-10) of 64.5%was seen at 12 months

This distinction matters not because B12 injections are inherently dangerous, but because the systems surrounding the injection determine how quickly and effectively a provider can respond if something unexpected occurs

Unscrew the drawing needle, drop it straight into your sharps container, and twist on a fresh injection needle

Getting B12 into the nervous system quickly helps prevent permanent nerve damage [3] [4]

However, given the results reported in previous studies (2,25,31-33) that used moderate/high doses of vitamin B12, it should be possible to demonstrate the non-inferiority of the oral treatment with this power level