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doi: 10.1362/146934711X589480 [DOI] [Google Scholar] 28.Paus R, Sevilla A, Grichnik JM

Mechanistic evaluations in laboratory contexts commonly include receptor affinity assessment, intracellular signaling cascade mapping, electrophysiological modeling, and structural conformation analysis within analytical systems designed for controlled observation

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It activates Gasdermin D (GSDMD)-dependent pyroptosis and inhibits SLC7A11 through the Stat3/p53/NRF2 pathway, thereby inducing ferroptosis ( Licorice chalcone A (Lico A), a key component of the traditional Chinese medicine Glycyrrhiza glabra, is a naturally occurring small molecule with various pharmacological effects