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These findings suggest that the pathological process of SUI may involve TGF-/Smad3 signalling

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Mitophagy, a selective form of autophagy, specifically targets damaged mitochondria for degradation, thereby preventing the release of ROS and subsequent cellular damage

Then these cells were treated via different concentrations of SP (cells/mL, 6.2 10 5 , 1.2 10 6 , 2.5 10 6 , 5 10 6 , 1 10 7 ) for 24 h

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Materials and methods Cell culture and lentivirus infection Cell lines including 293T, HeLa, Ishikawa, HEC-A, HEC-1B, AN3CA, and SPEC2 were obtained from the American Type Culture Collection (ATCC)