Be aware of these potential reactions and consult your healthcare provider if you experience any unusual symptoms
Biochemistry of B12-cofactors in human metabolism
GLP1: glucagon- like peptide1) Serotonin (5- hydroxytryptamine or 5HT) receptor modulation The nonselective serotonergic antiobesity drugs fenfluramine and dexfenfluramine have been associated with severe side effects like valvular heart disease and pulmonary hypertension
Formulations are not standardised concentrations vary by compounding pharmacy, which is one reason cross-clinic comparisons and published timelines are unreliable
This is helpful because it bypasses your digestive system, where B12 absorption often breaks down due to gut health issues or low stomach acid
A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss
