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Regulation of PGC-1, a nodal regulator of mitochondrial biogenesis

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People with digestive conditions such as Crohn's disease, celiac disease, or other inflammatory bowel conditions often have a compromised gut lining and cannot absorb oral B12 efficiently

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Chicken and fish have a moderate amount

How the condition is evaluated and managed Clinicians typically confirm B12 status with blood work serum B12, and often methylmalonic acid (MMA) and homocysteine, which rise when B12 is functionally low