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By three to six months of consistent use, significant improvement in overall skin tone evenness becomes apparent, with many users reporting that their hyperpigmentation has diminished by forty to sixty percent compared to baseline

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Although less common, minor side effects are redness or swelling at the injection site

Cu 2+ is the active principle of an endogenous substance from porcine cerebral cortex which antagonizes the anticonvulsant effect of diazepam