4, Supplementary Data 1 and 2)
doi: 10.1152/japplphysiol.01227.2005
Angiogenesis and growth factor signaling
Seminars in Immunopathology 44:209224 Griffiths C, Armstrong AW, Gudjonsson JE, Barker J (2021) Psoriasis Lancet 397:13011315 Gu Y, Zhang Y, Li M, Huang Z, Jiang J, Chen Y, Chen J, Jia Y, Zhang L, Zhou F (2021) Ferulic acid ameliorates atherosclerotic injury by modulating gut microbiota and lipid metabolism
Sequence 3: Sandwich method (for sensitive skin) Cleanse Light layer of moisturizer Apply retinol Apply peptide serum Final layer of moisturizer Best for: Reducing retinol irritation while still getting benefits Wait time between layers 1-2 minutes between products is ideal: Allows first product to absorb Prevents pilling or mixing on skin surface Maximizes penetration of each ingredient Don't wait too long: 5+ minutes unnecessary Skin dries out between applications Makes subsequent products harder to spread Morning vs evening application Evening routine (most common approach): Evening: Peptide serum + Retinol + Moisturizer Why: Retinol degrades with sun exposure
Diagnostic Testing Nutritional and Vitamin Testing : To identify any deficiencies that could be contributing to your condition