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The lyophilised powder is stored at -20 degrees C, protected from light and moisture

The spongy material is impregnated with a desired auris therapeutic agent and placed within the auris media so as to provide controlled release of the auris therapeutic agent within the auris media, or in contact with the round window membrane so as to provide controlled release of the auris therapeutic agent into the auris interna

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However, it is generally used in cycled protocols (e.g., 8-16 weeks) rather than continuous long-term therapy