Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma
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Still, in the process, it can create Superoxide, oxygen with too many electrons that is poisonous to everything around it, be it mitochondria, DNA, proteins, cell membranes, etc
doi:10.1080/13693780802056012
Many classical ferroptosis inducers, such as erastin and RAS-selective lethal 3, can target the xCT/GPX4 axis, and these inducers can trigger ferroptosis in cancer cells, suggesting they hold promise in the treatment of cancer [40, 42]
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