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SERMs are non-steroidal estradiol analogs with mixed agonist-antagonist effects on ERs and are used in osteoporosis and breast cancer treatment (Jordan, 2004)

Matsui et al., 2022)

The lack of next-day grogginess that most users report also suggests a cleaner mechanism that does not leave residual effects in the morning

Bcl-xL, a transmembrane molecule in the mitochondria, would inhibit apoptosis by preventing mitochondria oxidative contents, such as cytochrome c efflux to the cytosol and activating caspases

In addition, vitamin C and selenium are powerful radical scavengers contributing to the protection of cells from oxidative stress