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A double-blind, randomized controlled trial using 2% topical oxidized glutathione (GSSG) demonstrated significant skin-lightening effects after 10 weeks ( Watanabe et al., Clinical, Cosmetic and Investigational Dermatology, 2014 )

Graziani, V., Rodriguez-Hernandez, I., Maiques, O., & Sanz-Moreno, V

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Prior IA, Hood FE, Hartley JL