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Intradiscal administration stimulated an increase in the IVD heights and increased proteoglycan content in the IVD at 2, 4, and 8 weeks

Discontinuation due to adverse events was 5.9% in REDEFINE 1 and 8.4% in REDEFINE 2

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The hip is a ball and socket joint that allows a wide range of motion so that the human body is able to walk, run, climb stairs and perform everyday activities

B activation and suppresses the release of TNF-?, IL-1?, and IL-6, decreasing chronic low-grade inflammation linked to aging and tissue degeneration 4