Astrocytic uptake of -amyloid leads to it autophagic degradation, entrance of excess aspartate and ammonia into the urea cycle, increased putrescine and GABA production, with increased H 2 O 2 production and neuronal damage leading to cognitive deficits
Phillips, M
[DOI] [PubMed] [Google Scholar] 113.Mofarrahi M., Brandes R.P., Gorlach A., Hanze J., Terada L.S., Quinn M.T., Mayaki D., Petrof B., Hussain S.N.A
Specifications Summary Precautions & Notes Experimental behaviour of Epithalon is dependent on concentration, exposure duration, and experimental model Buffer composition, pH, and ionic strength may influence peptide stability and assay performance Literature reports are derived from heterogeneous experimental systems and should be interpreted accordingly Appropriate controls are recommended to distinguish specific from non-specific effects Intended strictly for laboratory research use
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S2)):S62S66
