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The BPC-157 Layer: Addresses the structural side (protecting the gut lining from the GI distress GLP-1s often cause, and potentially mitigating the severe muscle loss that accompanies rapid weight reduction)

Eder T, Weber A, Neuwirt H, Grunbacher G, Ploner C, Klocker H et al

500 mg daily is within standard supplementation ranges and generally considered safe for most healthy adults with normal liver function

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There are many far safer alternatives to coffee enemas