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[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Tlak Gajger I., Ribari J., Smodi kerl M., Vlaini J., Sikiri P

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conversely, an aggravated course of ischemic colitis was observed in L-NAME-treated rats, L-arginine-treated rats, and in IC rats (Tables 1-3 and Figures 1-25)

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The first involves binding with the Toll-Like Receptors (TLR) complex, which activates nuclear factor B and leads to the production of pro-inflammatory cytokines, including IL-1 and TNF-, as well as reactive oxygen species (ROS) and reactive nitrogen species (RNS)